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As another Trump term gets underway, pharma advisors get comfortable with...

What will President Donald Trump's team do on healthcare? Nobody knows for sure. That was the general agreement among the policy experts who advise the drug industry last week at the JP Morgan...

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UnitedHealth Group names Tim Noel as next insurance CEO

UnitedHealth Group has named a new CEO to lead its health insurance business, following the murder of the division’s former top executive in December. The role will be filled by Tim Noel, a company...

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Obesity biotech Aardvark files for IPO to advance oral drug

Aardvark Therapeutics filed for an IPO Thursday night, making it the sixth biotech in line this year for a potential listing on the Nasdaq. The San Diego biotech is trying to ...

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ALX Oncology to make case for accelerated approval with evorpacept in gastric...

ALX Oncology is forging ahead with a treatment approach that has long been abandoned by other drugmakers, eyeing a potential accelerated approval pathway for its CD47-targeting drug in gastric cancer...

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Moderna information chief to retire next month; Pharming looks to Flagship...

Moderna’s chief information officer Brad Miller is “retiring” in February, a company spokesperson confirmed to Endpoints News. His roughly two-year stint followed more than five years in top executive...

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Novo Nordisk’s amycretin prompts 22% weight loss in early obesity trial

Novo Nordisk’s subcutaneous form of amycretin achieved estimated weight loss of 22% at six months in a Phase 1b/2a clinical trial, the Danish company said Friday. The data are highly competitive ...

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AstraZeneca allocates $570M for Canadian expansion, looks to add 700 new jobs

AstraZeneca is looking to increase its presence north of the US border. The UK pharma said it is budgeting $570 million to expand its footprint in Canada, which will help create more than 700 new ...

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Boehringer merges cancer vaccine and oncolytic virus teams; Dantari sells off...

Plus, news about Madrona and Abdera: Boehringer Ingelheim combines two cancer units: The drugmaker is merging its cancer vaccine unit AMAL Therapeutics and its oncolytic virus team ViraTherapeutics,...

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The crucial obesity data to watch for this year

This year has already started strong for obesity drug developers, with Novo Nordisk, Metsera and Hengrui/Kailera all proclaiming clinical successes for GLP-1-based drugs. What might the rest of 2025...

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Takeda discontinues US supply of gout drug Uloric

Takeda has ended the manufacturing and supply of its gout drug Uloric in the US market as more patients turn to generic versions, the company confirmed to Endpoints News. “We have taken this decision...

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Upcoming PDUFA dates may be ensnared by Trump's pause at HHS, analyst says

President Donald Trump's communications pause for HHS, FDA and other health-related agencies could push some drug approval decisions to later dates, a Raymond James analyst told investors on Thursday....

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Merck and Eisai reveal late-stage fail for Keytruda and Lenvima in...

The combination of Merck’s Keytruda and Eisai’s Lenvima failed to prolong patients’ lives versus the comparator in another cancer study, but the companies say they are committed to the approach. In the...

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With Sam Altman’s help, Retro Biosciences eyes $1B to extend lifespan by 10...

Disease-reversal startup Retro Biosciences is aiming for a $1 billion funding round, a spokesperson for the company confirmed in a Friday email to Endpoints News. It would be one of the largest funding...

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Biogen paring back research efforts; Will Chinese biotechs threaten US...

Welcome to the weekend! We saw a flurry of health-related news from Washington DC this week as the Trump administration officially began its transition. Let’s go over it. On the day he was sworn into ...

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Agenus continues partnership talks for anti-CTLA-4 combo with new Phase 2 data

Five months after the FDA blocked its plans for accelerated approval, Agenus is moving ahead with discussions with potential pharma partners to chart a more conventional registrational path for its...

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Swarm Oncology launches with T cell therapy technology to treat solid tumors

A London-based biotech has emerged from stealth with a personalized T cell therapy platform that it says could create treatments that overcome the usual limitations of the approach. The main challenge...

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Eisai and Biogen win approval for once-monthly Leqembi dose

Eisai and Biogen scored an approval for once-monthly IV maintenance dosing of their Alzheimer’s drug Leqembi, as part of what they’ve said is an ongoing effort to make treatment more flexible for...

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Akero redeems its failure in severe MASH with longer-term data

Akero Therapeutics claimed a win in severe MASH on Monday morning, as the company’s candidate efruxifermin showed a 24% benefit on fibrosis reduction over placebo in a crucial mid-stage trial. ...

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Maze looks to lead IPO queue with $113M Nasdaq debut

Maze Therapeutics is eyeing a $113 million initial public offering a little under two months after revealing a $115 million Series D. The clinical-stage biotech — which has been through an FTC snafu ...

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Leerink Partners hires M&A bankers, grows health deals team

In a dramatic turnaround from bankruptcy court less than two years ago, Leerink Partners is now on the offensive and hiring away from rival banks to build out its M&A practice. The healthcare...

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