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Shanghai Bao, Sichuan Biokin file IPOs in Hong Kong; Disc's $200M offering

Plus, news about Rivus and Crown Labs: Two Chinese biotechs file for stock listings in Hong Kong: Shanghai Bao Pharmaceuticals and Sichuan Biokin Pharmaceutical join a queue of Chinese drug developers...

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Xilio reports handful of responses for combo in colorectal cancer

Xilio Therapeutics said its anti-CTLA-4 produced promising initial data in certain colorectal cancer patients enrolled in a mid-stage trial. But the drug’s future is uncertain as the company grapples...

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RFK Jr. says he’ll divest interests in CRISPR Therapeutics if confirmed for...

HHS Secretary nominee Robert F. Kennedy Jr. will divest his interests in several biopharma companies, including CRISPR Therapeutics and Dragonfly Therapeutics, if confirmed by the Senate, he said in a...

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Updated: Biogen enacts layoffs across its research unit

Biogen is laying off staff across its research unit, marking one of the most concerted strategic decisions from Jane Grogan since she took over the department. A company spokesperson said in a...

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Health navigation company Quantum Health lays off 4% of workforce

Longtime digital health company Quantum Health has laid off workers days after it appointed a new CEO, Endpoints News has learned. Founded in 1999, private equity-backed Quantum provides services for...

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Samsung Bio hits revenue high, secures largest contract to date

Samsung Biologics closed 2024 on several high notes, reaching its highest annual revenue to date — and just a week ago, securing its largest client contract so far. Samsung Bio pulled in a record-high...

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Chinese startup begins first clinical trial using CRISPR to edit cells...

A little-known Chinese biotech startup has zipped ahead of US companies in one of the gene editing field’s most competitive races. YolTech Therapeutics announced Monday that it started a clinical trial...

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J&J reinforces Caplyta blockbuster projections, won't shelve neuro prospects

Johnson & Johnson made the largest splash at this year’s JP Morgan Healthcare Conference, acquiring Intra-Cellular Therapies and its neuropsychiatric drug Caplyta for $14.6 billion. On the...

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Vanda loses constitutional fight over FDA's drug talks with competitors

The FDA dodged claims from Vanda Pharmaceuticals that it allegedly violated the US Constitution by recommending the same drug specifications for both Vanda and its generic competitors. The opinion,...

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AstraZeneca exec stresses Calquence's patent life ahead of next Medicare...

AstraZeneca says it plans to participate in the next round of Medicare negotiations under the Inflation Reduction Act. But this time around, the company says it’s dealing with a whole different set of...

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Teva’s MS drug and generics to add black box warning for anaphylaxis

The FDA has issued a new boxed warning for Teva Pharmaceuticals' multiple sclerosis drug Copaxone and generic versions marketed by other companies after some patients had serious allergic reactions....

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Anthos' detailed mid-stage data back its anticoagulant, but can the drug...

Anthos Therapeutics’ anticoagulant poses a lower risk of bleeding events than Bayer and J&J’s Xarelto when used to prevent blood clots in atrial fibrillation patients, full results from a mid-stage...

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BioMarin's James Sabry talks biotech M&A, dealmaking in 2025

SAN FRANCISCO — Not many biotechs survive beyond 25 years, let alone get multiple drugs approved and turn a profit. BioMarin Pharmaceutical has done all that, but finds itself navigating an unusual...

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Health Tech startup Innovaccer lays out its acquisition strategy

Innovaccer is buying up health tech companies with the goal of providing healthcare organizations with a simple place to go for a number of tools. The Silicon Valley-based startup sells tools to...

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FDA delays decision on Stealth’s Barth syndrome drug; TargetRx raises $50M

Plus, news about Valneva and Ab&B Bio-Tech: FDA delays decision on Stealth BioTherapeutics drug to April 29: The company’s elamipretide is being developed for Barth syndrome, a rare genetic...

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AbbVie partners with Neomorph in latest molecular glue deal

Neomorph is back at it again with another pharma collaboration. The startup, which is backed by Deerfield Management and the Dana-Farber Cancer Institute, secured another partnership for its molecular...

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What health tech wants from a Trump administration

We’re in the first week of the second Trump administration, and it’s becoming clearer how it might impact healthcare technology. Notably, President Donald Trump revoked the Biden Administration’s AI

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Catalent to make CAR-T for Galapagos; Kindeva gets $129M for nerve agent...

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. Catalent said it will manufacture Galapagos’ clinical-stage CAR T...

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Purdue, Sacklers reach new $7.4B opioid settlement after SCOTUS rejection

Purdue Pharma and the Sackler family have agreed to a $7.4 billion settlement in a longstanding legal battle over the nation’s opioid epidemic. The deal, announced Thursday, comes months after the...

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Teva, Astellas plan to participate in IRA drug price negotiations

At least three drugmakers say they will participate in the next round of Medicare negotiations under the Inflation Reduction Act, even though they continue to criticize the process as “price setting.”...

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