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GSK’s Blenrep combo meets key survival endpoint in Phase 3 multiple myeloma test

GSK continues to stack up wins to support Blenrep’s comeback, as the company teased new survival data from a late-stage multiple myeloma trial on Thursday. In people with second-line or later relapsed...

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Ascidian CEO Michael Ehlers leaves Apple Tree Partners for MPM BioImpact

Ascidian Therapeutics CEO Michael Ehlers is leaving the venture investor that serves as his home base and will join MPM BioImpact as an entrepreneur-partner on Monday, the investment firm told...

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Merck buys into PD-1/VEGF space as Summit comes for Keytruda

Summit Therapeutics and its Chinese partner Akeso have a few competitors now. Merck, the maker of the drug they're trying to beat, is entering the PD-1/VEGF space by handing down $588 million upfront...

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Merck KGaA’s life science unit is still feeling the Covid demand decline

A single Covid project that’s not been renewed made an earnings dent in Merck KGaA’s manufacturing arm in the third quarter, but the company is looking to reassure investors that orders are picking up...

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BeiGene rebrands as BeOne Medicines, dropping name's link to China

The global pharma company whose name rhymes with the capital of China wants people to know that it is not in fact a Chinese company, and is proposing a name change to more emphatically make ...

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As bluebird projects more commercial demand, the biotech continues to seek cash

Bluebird bio reported that 17 people with sickle cell disease have started the process of receiving its gene therapy Lyfgenia. Bluebird said in its third-quarter earnings Thursday that it recognized...

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Zai Lab aims to raise $200M; Kronos Bio to seek ‘strategic’ options

Plus, news about Allogene, Telix, Cullgen, Pulmatrix, Gilead, Innocoll, Durect and Sensei: Zai Lab’s $200M offering: The Shanghai-based drugmaker is selling shares the same week as announcing revenue...

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Novo Nordisk to phase out its production of human insulin pens globally

Novo Nordisk said Thursday that it plans to eventually halt all of its human insulin pen production globally, confirming an Endpoints News report from September. "We do continue to make human insulin ...

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New Zealand clears first clinical trial of epigenetic editing for hepatitis B

Tune Therapeutics announced Thursday that New Zealand health authorities are allowing the company to study its experimental epigenetic editing therapy for chronic hepatitis B in humans. It’s the first...

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Lonza expands bioconjugates factory; WuXi Bio adds capacity in Germany 

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. Lonza said it is expanding a facility in Visp, Switzerland, to house ...

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European Commission seeks biopharma feedback on Novo-Catalent deal — report

The European Commission is asking biopharma and manufacturing companies about their reaction to Novo Holdings’ proposed acquisition of Catalent, according to Reuters. While the EC declined to comment...

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Louisiana's Bill Cassidy named next chair of Senate health committee

Sen. Bill Cassidy (R-LA) will take over the Senate Health, Education, Labor, and Pensions Committee when the GOP gets control of the chamber in the next Congress, offering a change of pace on some...

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Arc Institute debuts AI model Evo, makes new CRISPR systems

Less than a decade ago, a slew of startups like Metagenomi and Mammoth Biosciences raised huge sums of money to advance CRISPR gene editing systems found in nature. ...

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European drug regulator reverses opinion on Eisai and Biogen's Alzheimer's drug

The European Medicines Agency has flipped its stance on Eisai and Biogen’s Alzheimer’s treatment Leqembi, recommending authorization in a narrower population than it previously considered. The agency's...

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Gilead to close Philadelphia and Seattle offices, make job cuts

More layoffs are hitting Gilead’s cell therapy wing, including the closure of a Philadelphia office. The company confirmed to Endpoints News that the office acquired in its Tmunity purchase is being...

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FDA says Merz's social media promotion with Nate Berkus is 'misleading'

Merz Therapeutics landed in hot water last month when the FDA said a social media promotion for its Botox rival Xeomin was “false or misleading." Now the company is trying to smooth things over. ...

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President-elect Trump selects Robert F. Kennedy Jr. to lead HHS

President-elect Donald Trump has picked Robert F. Kennedy Jr. to be his next HHS secretary, likely giving the government's most powerful healthcare post to a vaccine skeptic whose controversial views...

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Lilly sues US government over proposed 340B rebate model

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Adaptimmune to 'redefine' itself as a sarcoma biotech, cuts a third of staffers

Adaptimmune is slashing its headcount as part of a broader company restructuring aimed at saving $300 million over the next few years through 2028. The company said it will axe 33% of its employees in ...

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ALX Oncology hires Genentech, Mirati vet as new CMO; After Carmot, Heather...

ALX Oncology has found a new chief medical officer, tapping Alan Sandler for the role. Sandler comes to ALX from Mirati, where he was CMO before its acquisition by Bristol Myers Squibb earlier this...

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