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Boehringer Ingelheim wins jury verdict in Zantac retrial in Illinois

An Illinois jury ruled in favor of Boehringer Ingelheim in Zantac litigation brought by two prostate cancer patients, the company confirmed. The verdict followed two mistrials in ...

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Emalex clears Phase 3 for Tourette syndrome, will seek FDA approval

Emalex Biosciences said its daily oral tablet helped reduce relapses for children and adults with Tourette syndrome in a Phase 3 study, and now plans to take the drug to regulators for approval. The...

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Compounders sue FDA over end of semaglutide shortage

Drug compounders have sued the FDA to put the weight loss and diabetes drug semaglutide back on an official shortage list, fighting a regulatory decision that imperils the companies' business. “If ever...

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Candel's viral therapy shows promising survival in small pancreatic cancer study

To Candel Therapeutics CEO Paul Peter Tak, the biotech’s viral immunotherapy has passed the "bloody obvious test" in pancreatic cancer, and it’s preparing to start a larger trial next year. The biotech...

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Leo Pharma says its yearslong makeover is about to pay off

For the first time since 2018, dermatology-focused Leo Pharma projects that it could turn a profit this year. Its Wednesday guidance comes on the heels of a broad multiyear restructuring — a plan ...

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Court orders CVS to comply with the FTC’s PBM-related investigation

The Federal Trade Commission is continuing its investigation into anticompetitive PBM practices, with a new court order that will require CVS Health to share more requested documents about its PBM....

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Eikon raises $351M Series D, pipeline advances to Phase 3

One of biotech's best-funded startups has just raised a huge new round to take its lead drug into final-stage testing. On Wednesday, Eikon Therapeutics announced a $351 million Series D round, one of...

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Merck says Keytruda could be up next for IRA price cuts

Merck said its “once-in-a-lifetime” drug Keytruda could be subject to price reductions under the Inflation Reduction Act, which would lead to a decline in sales. It expects Keytruda to be chosen for ...

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Ginkgo uncertain over the future of US government funding, stock drops

Ginkgo Bioworks’ stock $DNA fell by around 13% premarket Wednesday after the company dampened its 2025 sales forecast. “We are being conservative with our revenue guidance in 2025 given uncertainty...

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Lilly says it will invest $27B into US drug manufacturing

Eli Lilly is continuing to invest big in US pharma manufacturing, with the addition of three new domestic API sites and another injectables site, creating as many as 13,000 new jobs, the company...

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Harbour BioMed inks deal up to $395M; ORIC refines plans for two drugs

Plus, news about Idorsia, Enveda, Zymeworks, BerGenBio and Ignota Labs: Harbour BioMed does another deal: The Shanghai-based biotech’s subsidiary, called HBM Alpha Therapeutics, inked a pact with an...

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Regeneron, two Chinese biotechs tout promise of their hearing loss gene...

Several small clinical trials have demonstrated that gene therapies have restored hearing in children with a rare form of genetic deafness. In an update at the Association for Research in...

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AstraZeneca’s SERD hits primary endpoint in late-stage trial, but first-line...

AstraZeneca wasn't expected to have data from the Phase 3 trial of its oral SERD until the second half of this year so the positive interim results that the UK drugmaker

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Regeneron shakes up accelerated approval plans for lymphoma bispecific

Regeneron is now expecting an accelerated approval decision this summer on its T cell engager for one form of lymphoma, while it's giving up on accelerated approval for a different form of the disease....

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Medicare spending on set of diabetes drugs skyrocketed — report

The use of a subset of common diabetes drugs skyrocketed in the US Medicare program over a five-year period ending in 2023, according to a new report from the HHS inspector general. The

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FDA meeting to pick next winter's flu shot is canceled

A meeting by a panel of science advisors to choose flu strains to include in a vaccine for next fall has been canceled on short notice, according to a member of the committee, raising concerns ...

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Sorriso Pharmaceuticals outlines Phase 1b ulcerative colitis data for oral...

Private startup Sorriso Pharmaceuticals laid out Phase 1b data at a medical conference last weekend as part of its effort to bring an oral antibody to market for IBD patients. The results come after...

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Kallyope quietly reports Phase 2 obesity data, begins mid-stage migraine trial

Kallyope, a New York City biotech that has raised about $480 million over the past decade, quietly released results of its Phase 2 study in obesity in ...

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Merck mulls new site in Delaware; Granules India buys peptide CDMO

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. Merck has received a $30 million strategic fund from the state of...

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Bayer CEO Bill Anderson previews 2025 turnaround plans

Something changed for Bill Anderson when he turned 50. He was ascending the ranks of Roche’s Genentech, but the Texas native felt like he was stuck in the same loop year after year. The company ...

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