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After passing on M&A offers, Abcuro raises $200M in bid to become commercial...

After quickly enrolling its pivotal trial and recruiting more patients with a rare muscle disease than anticipated, Abcuro went to its board to explore a $60 million to $80 million fundraise. That...

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Cerula Care raises $3.7M to support cancer patients’ mental health

Cerula Care has raised $3.7 million in seed funding to help patients better fight cancer by checking in on them, supporting their mental health and helping with practical needs such as nudges to take...

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Odyssey underwent layoffs; GSK to move vaccine R&D site to Cambridge

Plus, news about Aligos Therapeutics, Terrain Biosciences, the Gates Foundation and Neuphoria Therapeutics: Pre-IPO, Odyssey Therapeutics conducts layoffs: The Boston-based biotech let go of an...

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AbbVie pens another T cell engager deal, this time with Xilio

AbbVie and Xilio Therapeutics are partnering to make “masked” T cell engagers, which they hope will be safer than currently available options. Xilio said Wednesday the collaboration would develop new...

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AnaptysBio gets a mid-stage win for PD-1 drug in rheumatoid arthritis

AnaptysBio trumpeted a Phase 2b success in rheumatoid arthritis Wednesday morning after a similar program from Eli Lilly was discontinued late last year. Anaptys’ program, known as rosnilimab, hit its...

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Pfizer wins approval in new indication for blood cancer drug Adcetris

Pfizer secured an eighth indication for its blood cancer drug Adcetris after the FDA approved its use in adults, in combination with two other medications, to treat relapsed or refractory large B cell...

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What CVS is doing about high medical costs

CVS Health ended 2024 as it started, with high medical costs in the company’s insurance business chipping away at its bottom line. The healthcare giant late last year tapped new CEO David Joyner to...

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Kaiser Permanente calls on FDA and Congress to firm up accelerated approval...

While FDA is implementing new accelerated approval reforms, Kaiser Permanente says the reforms do not go far enough. The health system, which owns an insurer, said the agency needs to work with...

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NIH’s funding cut plan poses challenges for researchers despite court halt

An NIH cap on indirect cost payments for grant recipients is casting a shroud of uncertainty for research universities despite a judge’s order to block it. A federal judge this week

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Novo's weight loss drug helps curb some drinking habits, small study shows

New research from the University of North Carolina-Chapel Hill found that Novo Nordisk’s weight loss drug may help people curb their alcohol consumption. Results from the small Phase 2 study

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Ex-DeepMind scientist launches AI biotech Latent Labs with $50M

Simon Kohl turned an internship at Google DeepMind into a key role in building AlphaFold2, the Nobel Prize-winning AI model that predicts the structure of proteins. Now, Kohl is venturing out on his...

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Roche sends experimental CNS drugs to Newleos, a new biotech backed with $93.5M

Newleos Therapeutics emerged Thursday with $93.5 million and a bundle of oral small molecules that it licensed from Roche, further demonstrating that the pharma-to-startup pipeline for CNS drugs is...

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Hunger-suppressing biotech Aardvark raises $94M in IPO

Aardvark Therapeutics, a biotech looking to address hunger rather than appetite for metabolic diseases, will go public on Thursday with a $94 million debut on the Nasdaq. The San Diego-based biotech...

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Sanofi faces $250M charge after J&J-partnered vaccine flunks late-stage test

Sanofi has been hit with a $250 million impairment charge after an E. coli vaccine candidate it was developing with Johnson & Johnson failed to clear a Phase 3 study. An independent data monitoring...

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Neumora replaces CEO with ex-chief Berns after trial failure

In a surprise move Thursday, Neumora remade its executive team and brought back its former CEO, following last month's failure of the brain health biotech's first big clinical test. Paul Berns, who ...

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Idorsia’s Tryvio licensing negotiations collapse amid cash squeeze

Idorsia’s plan to hand over the global rights to its blood pressure drug Tryvio has ended in disappointment after a deal announced in November fell through. The Swiss drugmaker said Thursday ...

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Allay Therapeutics raises $45M for ongoing Series D; Encoded’s layoffs

Plus, news about Pliant Therapeutics, Blueprint Medicines, Galapagos and Atai: Pain biotech raises $45M: Allay Therapeutics, which is developing non-opioid analgesics pain drugs, held the first close...

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Syngene CEO departs; Lilly and AdvanCell sign radiotherapy partnership

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. The CEO of India-based CDMO Syngene, Jonathan Hunt, has left the role...

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Agios’ Pyrukynd succeeds in key trial of rare red blood cell disorder in kids

Agios' blood disease treatment Pyrukynd passed a Phase 3 study in PK deficiency in children who do not regularly receive blood transfusions. The readout arrives after Pyrukynd last year failed to meet ...

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Kennedy is confirmed by Senate as Trump's HHS secretary

The Senate on Thursday confirmed Robert F. Kennedy Jr. as Secretary of Health and Human Services, putting a longtime anti-vaccination advocate at the helm of the nation’s health agencies that monitor...

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