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Coherus makes final, $483M pivot away from biosimilars

Coherus BioSciences' stock surged on Tuesday after the company announced plans to sell off the last biosimilar in its portfolio. Intas Pharmaceuticals has agreed to purchase Coherus’ Neulasta...

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Applied Therapeutics gets FDA warning letter for rare disease drug

Following the FDA's rejection last week of Applied Therapeutics' experimental drug for a rare disease called classic galactosemia, the company announced Monday that it also received a warning letter...

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Eli Lilly, Pfizer stress independence of telehealth partners in response to...

In response to lawmakers' concerns, Pfizer and Eli Lilly said last week that they do not influence telehealth partners and their clinicians to prescribe their brand-name drugs. Both companies launched...

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Kiromic and SEC settle over undisclosed clinical trial holds

The SEC said Tuesday that it settled charges filed against Kiromic BioPharma, a tiny immuno-oncology startup based in Texas, for failing to disclose clinical holds on two experimental cancer drugs...

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GSK terminates Phase 2 trial of HBV therapeutic vaccine

GSK has axed a Phase 2 study of a chronic hepatitis B therapeutic vaccine, adding to a string of treatment R&D hurdles for the liver infection. The termination of the study of GSK3528869 was the ...

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Lilly removes body mass ranges from FDA label for weight loss drug

Eli Lilly has removed the commonly used clinical measure of body mass index from the FDA label for its weight loss drug Zepbound, a move that could give physicians greater leeway to decide who should ...

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On heels of MariTide data, Danish obesity biotech discloses €80M Series A

Versant is out with its third obesity biotech of the year, leading an €80 million Series A for Antag Therapeutics, a Danish company developing a drug that uses a similar approach as Amgen's...

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GSK makes another ADC deal, this time with BioNTech's partner DualityBio

GSK is returning to China for another antibody-drug conjugate deal, and it's tapping into a company that already has alliances with BioNTech, Adcendo and others. The UK pharma is ...

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Lilly wins head-to-head weight loss trial against Novo Nordisk

The market for first-generation weight loss treatments has been dominated by two major players, Eli Lilly and Novo Nordisk. But new data provide the clearest evidence yet that one may have an edge. On...

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Atea blueprints Phase 3 for hepatitis C combo after mid-stage win

Atea Pharmaceuticals touted data from a mid-stage trial studying its hepatitis C drug combo on Wednesday, announcing that it had hit both safety and efficacy primary endpoints. The 275-patient trial...

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Dewpoint partners its ALS program, eyes JPM to raise a Series D

Molecular condensates startup Dewpoint Therapeutics has signed on its latest partner, this time forging a future for its ALS program with Mitsubishi Tanabe Pharma Corporation in a pact worth up to $480...

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Ro’s weight loss business more than doubled in the last year. Now it’s trying...

With direct-to-patient services for obesity drugs facing scrutiny, the telehealth startup Ro is trying to prove that its online weight loss program is up to snuff. To that end, the startup released ...

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GSK partners with Rgenta on RNA-targeted small molecules for oncology, other...

GSK will team up with Boston-area biotech Rgenta Therapeutics to create oral small molecules that target RNA, the companies said Wednesday morning. The duo will discover and develop splice modulators...

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Updated: CEO of UnitedHealth insurance unit shot and killed in New York in...

UnitedHealthcare CEO Brian Thompson was shot and killed in Midtown Manhattan Wednesday morning ahead of the insurer's investor day, according to the company and police. The New York Police Department...

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GeneDx bets that rare disease data can aid drug discovery

Two years ago, GeneDx was teetering. The genetic testing company had laid off 33% of its staff, shares were down 90% from a year prior, and some investors were skeptical of a turnaround plan. ...

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Relmada's rapid-acting NMDA depression drug expected to fail second Phase 3

Relmada Therapeutics said Wednesday morning that a Phase 3 study testing its major depression drug, REL-1017, is likely to fail, cratering its stock price. The study’s data monitoring committee said...

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AstraZeneca's new EVP of international amid China investigation; Janux’s...

Plus, news about Arrakis, Eli Lilly, Everest Medicines, Teva, Rondo Therapeutics, Trevi Therapeutics, Foresee Pharmaceuticals and Revolution Medicines: AstraZeneca taps new leader to run China...

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Novavax sells Czech facility to Novo Nordisk for $200M to cut costs

Novo Nordisk is buying a vaccine manufacturing factory from Novavax for $200 million to expand production of its current and future mammalian-based products, a spokesperson for the Danish drugmaker...

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Sickle cell gene therapies included in new Medicaid access model

The Biden Administration said Wednesday that it has secured agreements with Vertex Pharmaceuticals and bluebird bio for their sickle cell disease gene therapies to be the first in a new access model...

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Trade group tells FDA that semaglutide is not too 'complex' for compounding

The Alliance for Pharmacy Compounding told the FDA last week that Novo Nordisk's weight loss medicine semaglutide is not too difficult to compound, pushing back against the Danish pharma's arguments...

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