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AI-focused biotech insitro cuts 22% of staff, citing 'tumultuous market'

The AI-focused biotech insitro has laid off 22% of its workforce, the company said in a Thursday statement. Founded in 2018 by CEO Daphne Koller, a leading computer scientist at Stanford University,...

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Illumina forecasts $85M in tariff costs, decrease in China sales

Illumina estimates about $85 million in costs this year related to tariffs on its DNA sequencing products, the company said Thursday during its quarterly earnings report. In addition, it expects China...

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Takeda announces handful of pipeline cuts in effort to ‘pivot resources’

Takeda revealed a handful of pipeline cuts in its fourth-quarter earnings results on Thursday, as the company focuses its attention on six late-stage programs it says could deliver billions of dollars...

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Illumina confirms SEC has closed investigation into $8B Grail deal

Illumina on Thursday said the SEC has closed its investigation into the company's $8 billion purchase of Grail and doesn't intend to pursue enforcement action, confirming Endpoints News' reporting...

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AI biotech Insilico Medicine goes for third attempt at Hong Kong IPO

Insilico Medicine is hoping to ride a recent wave of momentum for biotech startups on the Hong Kong Stock Exchange. The biotech, headquartered in Cambridge, MA, filed for ...

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Corvus' Phase 1 atopic dermatitis data prompt stock rally

Corvus Pharmaceuticals reported new Phase 1 data in atopic dermatitis that sent its stock price {$CRVS} up by as much as 35% premarket Friday. The results come from three cohorts of ...

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Lilly shuffles key executive positions; Mikael Dolsten takes another...

→ Eli Lilly is making some adjustments to its team: Patrik Jonsson and Ilya Yuffa will trade places as Jonsson becomes president of Lilly International, while Yuffa succeeds Jonsson with an ...

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Introducing the new Endpoints profile experience

We’ve got some exciting upgrades coming to the Endpoints platform this year. Today, we’re launching the first step — a new profile experience — which will serve as a single place to access and manage...

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Lonza says its US-based sites are in high demand as pharma tariffs near

Lonza said on Friday it does not expect any “material financial impact” from current and potential pharma-specific tariffs, as the Swiss CDMO fields inquiries for its US-based facilities ...

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Revolution’s KRAS drugs appear competitive in several lung cancer settings

Revolution Medicines revealed new data that suggest its closely watched KRAS-targeting cancer programs could be highly competitive with similar therapies already on the market. The biotech’s shares...

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AstraZeneca reports Phase 3 win for Imfinzi; Roche to build new manufacturing...

Plus, news about Sanofi, IGM Biosciences, Eli Lilly, Purdue University, Minghui, Qilu, Sirius Therapeutics, Keros Therapeutics, Palatin and Leo Pharma: 💉AstraZeneca touts Imfinzi Phase 3 win in...

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Iovance stock plummets after lowered full-year guidance

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Chronic care startup Omada Health files to go public

Virtual diabetes and chronic care startup Omada Health filed to go public on Friday, making it the second digital health company to do so this year as the sector shows signs of picking up after ...

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Makary names Vinay Prasad CBER chief; Q1 earnings report; More on “Most...

Welcome back to Endpoints Weekly — thanks for starting your Saturday with us. It was a busy week in the biopharma world. FDA Commissioner Marty Makary picked a new CBER chief to replace Peter Marks,...

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Trump confirms 'most-favored nation' drug price plans

President Donald Trump said he'll take executive action to have the US pay no more than other countries for drugs, a move that would expand price controls and is almost certain to generate strident...

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Lilly says further head-to-head trial data back Zepbound over Novo’s Wegovy

Eli Lilly said Sunday that new data on Zepbound show the GIP/GLP-1 dual agonist is a better weight loss drug than Novo Nordisk’s Wegovy. Almost 65% of obese or overweight people treated with Zepbound...

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Trump signs ‘most favored nation’ order to try to lower US drug prices

The White House plans to force down prices of drugs sold in the US by threatening to tie costs to rates paid by other countries, a directive that could have huge impacts but is almost ...

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FDA clears in vivo blood stem cell editing trial; Abeona's $155M PRV sale

Plus, news about CytomX, Valneva, Lenz and Lotus Pharmaceutical: 🧪 After China, US greenlights first trial of in vivo blood stem cell editing: Ensoma

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#EASL25: Vir’s hep B disappointment, new data on Ipsen's Iqirvo

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Exclusive: Patrick Hsu’s startup Stylus Medicine launches, looks beyond...

Stylus Medicine, an ambitious startup founded by Patrick Hsu, has raised $85 million to develop a suite of technologies that it believes will help solve some of the biggest and most competitive ...

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Roche could rethink $50B US expansion plan if new policies 'harm' operations

Roche said its $50 billion promise to expand its manufacturing footprint in the US has the potential to be “reassessed” — the same day the Swiss pharma added further details on how it would spend part ...

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Republican tax cut bill includes PBM, drug price negotiation changes

The latest version of a massive and wide-ranging tax cut bill includes several pro-pharma reforms related to pharmacy benefit managers and the way the drug price negotiation program deals with orphan...

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Trump's drug price plan is light on details, may have little impact

The White House's plan to realign US drug prices with similar high-income countries has ignited a wave of questions about how or even if drug companies will come to the table and work with the ...

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Pharma investors brush off Trump’s ‘most favored nation’ plan as stocks rise

President Donald Trump on Monday made a sweeping promise to bring down drug prices and stop pharma companies from taking advantage of the US. Wall Street seems unfazed. As details of Trump’s

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